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melatonin 400mg suppository

Zetpil™ Melatonin 400mg SR Suppository

$189.95

  • Most powerful antioxidant known to mankind.
  • Supraphysiologic dosages (higher amounts than the body can make or ingest through diet) MUST be achieved in order for melatonin to exert its antioxidant effect.
  • May support prevention of and treatments for cancer, heart disease, aging, diabetes, autism, and arthritis.*
  • Melatonin is a diverse free radical scavenger that has the ability to squelch all known free radicals and cross all cellular structures, including the mitochondria.*
  • Melatonin may be able to prevent and treat conditions caused by mitochondrial dysfunction.*
  • Melatonin forms stable metabolites which are also free radical scavengers, resulting in a free radical scavenging cascade, unique only to melatonin.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Zetpil™ Suppository Advantage

Zetpil™ delivers nutrition via the rectum with the use of suppositories that have a unique, all- natural formulated base that has revolutionized not only this mode of delivery, but also the ability to obtain nutrients in a far more efficacious method.  These suppositories are a result of combining natural ingredients with a non-irritating, rapid melting (5-6 minutes), readily absorbable (superior retention), antioxidant base material (free radical scavenging ability) and delivers the nutrients directly into the bloodstream in less than 20 minutes in a highly effective manner. Oral supplements are exposed to the hazards of stomach acid, digestive enzymes, food-related breakdown, first pass metabolism, and other bioavailability issues in the gastro-intestinal system.

Additionally, many raw materials simply have a very low bioavailability , and only achieve around 10% or less (commonly <1%) absorption rates, even if the patient is in optimal health condition. Compromised health, age, or certain conditions that result in inability to take oral nutrients often preclude these patient populations from obtaining the necessary nutrition to stay healthy which often exacerbates chronic health issues.

Zetpil™ suppositories, as well as deep penetrating creams, are a NOW solution to delivering the necessary nutrients to patients, on a daily basis, that is both easy, comfortable and cost effective. The safety and noticeable effectiveness of these products will far outweigh any initial hesitation you have regarding this mode of delivery.

**NOTE: Melatonin currently is unavailable as intramuscular injections, nebulizer (nasal mist) or by intravenous administration anywhere in the world. Accordingly, the Zetpil ™ Melatonin Suppository is the only therapeutic melatonin option currently available.


What makes our Melatonin product different?

The Zetpil™ difference lies in our product’s ability to achieve therapeutic dosages via an alternate mode of delivery.  The impression of most lay people and physicians alike that the low oral dosages (2-10mgs) that help individuals sleep will also be able to exert melatonin’s powerful antioxidant effect is false.  Nothing could be further from the truth! 

Oral delivery of melatonin results in extremely low dosages absorbed as a result of low oral bioavailability, GI and liver metabolism of the compound, and lack of systemic circulation of therapeutic dosages.  It has been repeatedly proven in the research that dosage levels that trigger antioxidant activity cannot be achieved with oral delivery of melatonin.  Supraphysiologic dosages (higher amounts than the body can make or ingest through diet) MUST be achieved in order for melatonin to exert its antioxidant effect.  Research has hailed melatonin as the closest thing to a universal panacea (ie: cure for all ailments) ever researched by modern medicine which was the driving force for Zetpil™ to develop its Melatonin suppository and capitalize on all its potential health benefits.

What makes this product truly revolutionary is that therapeutic dosages of pharmaceutical grade Melatonin, embedded into our proprietary suppository base, can be delivered directly into the blood stream (via the many blood vessels that exist in the rectum),  potentially affecting an elevation of the serum melatonin levels.  Suppositories offer patient-friendly, cost-effective, and a natural, safe opportunity for repeated dosages of melatonin to be taken indefinitely! This breakthrough form of delivering melatonin truly raises the bar in effective antioxidant therapy for the patient population who desire an effective, affordable and potent antioxidant solution.

 


What is Melatonin?

Melatonin (N-acetyl-5-methoxytryptamine) is an indolamine (neurotransmitter) which is synthesized not only within the pineal gland in the brain, but has also been shown to be synthesized in many other parts of the body including, but not limited to, organs, the eye, gut, bone marrow, skin and immune cells.  The role of melatonin in circadian rhythm disturbances and sleep disorders is well established.

However, in the last several years, over 4,500 publications in peer-reviewed journals in the National Library of Medicine have confirmed melatonin, at higher dosages, to be the most powerful antioxidant in existence and the only universal free radical scavenger.

Patient and professional understanding of this unique and powerful signaling molecule must extend beyond jet lag and sleep aid. Some of its multiple beneficial functions may include powerful antioxidant, DNA protectant, immune function gatekeeper, and a natural oncostatic (anti-cancer) molecule. The research conducted in these regards has unequivocally documented melatonin’s ability to detoxify ALL harmful free radicals which cause molecular damage leading to disease and dysfunction.