Zetpil™ delivers a 21st Century Solution to a Widespread Global Problem

Are you:

  • Diagnosed with a type of anemia?
  • Tired of being tired?
  • Tired of waiting for your levels to drop low enough to warrant treatment?
  • Tired of oral Iron supplements that simply DON’T WORK?
  • Tired of the time, expense and hazards of IV Iron replacement therapy?
  • Suffering from Chronic Conditions that preclude you from taking Iron due to nausea and vomiting? (ie: chemotherapy)
  • Unable to take Oral Supplements?

 

Anemia- Still a Problem in the 21st Century:

Anemia is a signal that your body has a shortage of hemoglobin, the protein in red blood cells which delivers oxygen to tissues and organs.  Anemia occurs if the body produces too few red blood cells, loses too many of them, or if red blood cells are destroyed faster than they can be replaced.  There are nearly 100 different types of anemia with many causes.  The most common causes are genetic/serious chronic diseases, side effects from prescription drugs, vitamin or iron deficiency, or significant blood loss.

This is a common condition which can negatively affect your quality of life by impairing immunity and reducing physical and mental capacities.  Although there are treatments, most often anemia is misdiagnosed, under-identified, and overlooked as a serious medical condition.  Government statistics indicate that 3.4 million Americans are anemic, but in all likelihood those numbers are far greater.   Worldwide, iron deficiency is a major public health problem with enormous social and economic costs.

People at risk for anemia or iron deficiency include the elderly, menstruating/pre-menopausal women, diabetics and critically ill patients.  Those people with malnutrition, absorption issues, cancer, heart or chronic kidney disease, IBD, AIDS, Hepatitis C or Rheumatoid Arthritis also frequently suffer from anemia and its associated side effects.

Is Anemia Treatable?

Anemia is definitely treatable, but the sooner it is discovered, the better because restoring iron levels often takes a long time.  Treatments depend on the cause of the anemia in addition to other specific patient issues.  For example, diet and nutritional supplements may be prescribed for iron/vitamin deficiency-related anemia while more aggressive IV iron therapy may be warranted in the case of a severe injury that caused significant blood loss or in the case of a chronic disease which continues to deplete iron levels.

Problems Associated with Oral Iron Replacement Therapy:

However, oral iron replacement therapies are often extremely unsuccessful and have a low rate of patient compliance, and subsequently low success rates. For example, the absorption rate of oral non-heme iron supplements, such as ferrous sulfate or ferrous fumarate, can be as low as 2.9% on an empty stomach and 0.9% with food.   Some iron-rich foods are poor sources of the mineral because other compounds render it non-absorbable.

In addition to the many factors that can contribute to poor iron absorption, many individuals are sensitive to oral iron supplements. Since the best absorption of iron supplements occurs on an empty stomach, the ingestion of oral iron can often cause stomach upset. Other side effects are bloating, stomach cramps, chest pain, clammy skin, constipation, heartburn, nausea, bluish lips or fingernails and vomiting. Iron can also cause stool to turn black in color.  However, in most cases this is merely a sign of unabsorbed iron.

Problems Associated With Intramuscular or Intravenous Iron Replacement Therapy:

The use of intramuscular or intravenous therapy is reserved for individuals that are severely anemic. The use of Intramuscular injections, although still done, has fallen into disfavor by many in the medical community because intramuscular iron injections requires a relatively high degree of skill and care to administer, are usually quite painful, patients often experience permanent scaring over the site of the healed injections, and are no safer than intravenous therapy.

Intravenous iron therapy also poses risks and potential side effects and is generally reserved for patients who are iron deficient with hemoglobin levels at or below 8.0 g/dl. In the case of chronic malabsorption, individuals with chronic Iron deficiency Anemia (IDA) who receive intravenous iron dextrin therapy are often unable to maintain their levels with follow-up daily doses of oral iron supplements and therefore require repeated intravenous iron treatments as they develop iron deficient anemia over and over again.

Prior to the development of the Zetpil™ Multivitamin & Mineral with Iron, an individual with recurrent iron deficient anemia had no option but to suffer while they progressively became sicker and until their levels again were low enough to justify treatment with intravenous iron replacement treatments. This slow and progressive drop in iron levels and hemoglobin often takes months, while the iron deficient individual suffers from the debilitating symptoms of iron deficient anemia. As you might imagine, this combination of chronic illness and repetitive therapy takes both a physical and emotional toll.

Another complication that occurs in individuals who are required to undergo recurrent intravenous iron therapy to treat this “anemia rollercoaster” is the collapse of the veins used for the intravenous therapy. Often these patients will require the use of either a Peripherally Inserted Catheter (PIC) or a Central Venous Line (CVL) with all the discomfort, inconvenience and complications associated with those procedures.

Further dilemmas occur in individuals who are clearly anemic and significantly symptomatic but the levels are not low enough (Hemoglobin at/or below 8 g/dl) to warrant exposing the individual to the risks and potential side effects of intramuscular or intravenous iron replacement therapy. However, because these individuals do not respond adequately to oral iron replacement therapy, these individuals are trapped in the painfully symptomatic and debilitating world of permanent iron deficiency anemia.  This is a common problem for those who suffer from medical conditions such as Celiac Disease, Crohn’s Disease, Cystic Fibrosis, Fibromyalgia, Restless Leg Syndrome, cancer, or Gastric Bypass patients where nutrient malabsorption is a problem.

Until the development of the Zetpil™ Multivitamin & Mineral with Iron Suppository, an individual’s options with these conditions were quite limited, and often resulted in futile attempts to raise the iron levels and treat the iron deficiency with higher and higher dosages of oral supplements (triggering many of the side effects associated with higher oral iron supplements).  Many even come to believe that there is nothing that can be done.

Zetpil™’s Multi-Vitamin and Mineral with Iron ACTUALLY WORKS!

One Zetpil™ customer has spent decades battling this issue, frustrated by ineffective products, costly and repeated IV therapy, and overall health that simply continued to deteriorate on multiple levels.  Her story illustrates the power of this product for those suffering from anemia and iron deficiency.

Here are her words:

I found out that I was not absorbing iron very well. Apparently I never did, but the doctors never found out until I started bleeding very heavily for weeks at a time! I was put on iron supplements for a while, but they didn’t work. The only solution was to get iron by infusion at the hospital! I did it for a while, but then I decided I didn’t want to keep going to the hospital and stay a few hours while they infused me.

I then began using the Zetpil™ Multi-Vitamin and Mineral with Iron suppositories.

After only a month and a half I can already feel improvements, including I’m warmer, my hands and feet are no longer cold and I’m not getting out of breath all the time anymore.  I got bloodwork done after only being on the Zetpil™ Multi-vitamin and Mineral with Iron for 45 days and I am so happy with the results! My blood count went up as much as it did in six visits to the hospital for iron infusions!   I have great hopes for the future now.

 

Zetpil™ delivers with a 21st Century solution:

Current attempts to resolve anemia and iron deficiency are wholly unsuccessful and not patient-friendly.  Treatments which cause further side effects and further exacerbate people “just not feeling well” need to be replaced with easy, patient-friendly, cost-effective, convenient and most of all EFFECTIVE options to end this common yet widespread health problem.

This solution is LONG OVERDUE, and those who continue to suffer from anemia and iron deficiency finally have an opportunity to make a real difference and reverse the condition that diminishes their quality of life on a daily basis.

Zetpil™’s Multi-Vitamin and Mineral with Iron suppository represents a quantum leap forward in effective delivery of iron supplements for individuals suffering from iron malabsorption.  Equally important as the iron, Zetpil™ formulates its iron supplement with the vitamin and mineral cofactors which are REQUIRED to facilitate the biochemical reactions to convert and metabolize iron adequately.

Although this commonsense approach seems simple enough, it has taken our research team 5 years and countless hours of tireless research to develop an all-natural suppository that was safe, effective, comfortable, hypo-allergenic and essentially side-effect free.  This innovative suppository delivers:

  • the highest quality vitamins and minerals in a specialized combination of highly absorbable forms of iron,
  • the most bioactive forms of the B vitamins and the specialized forms of B12, pure methylcobalamin and adenylcobalamin,
  • specialized mineral micronutrients, and
  • the specific amino acids needed in the conversion of elemental iron to resolve Iron Deficiency Anemia (IDA) as well as anemia due to a deficiency of other essential nutrients.

We are proud to offer a product that can drastically improve the lives of those living with iron deficient anemia.  We are confident that you will find this solution cost-effective, easy, patient-friendly and above all, noticeably effective!

 

Use promotional code “Iron5” from now through the end of October to receive $5 off any Multi-Vitamin and Mineral with Iron suppository.

http://www.zetpilnutrition.com/product/zetpil-multivitamin-mineral-with-iron/

 

References:

Management of Iron Deficiency Anemia

Gastroenterol Hepatol (N Y). 2015 Apr; 11(4): 241–250.

Kristine Jimenez, MD, et al

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836595/

Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review

Medicine (Baltimore). 2015 Jun; 94(23): e963

Ole Haagen Nielsen, MD, PhD, et al

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616486/

Iron Deficiency Anemia: A Common and Curable Disease

Cold Spring Harb Perspect Med 2013 Jul; 3(7): a011866

Jeffery L. Miller

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685880/

High Prevalence but Insufficient Treatment of Iron-Deficiency Anemia in Patients with Inflammatory Bowel Disease: Results of a Population-Based Cohort

Gastroenterol Res Pract 2012; 2012: 595970

Claudia Ott, et al

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413990/

Cancer-related anemia: biological findings, clinical implications and impact on quality of life

Oncology 2005; 68 Suppl 1:12-21

Blohmer JU, et al

http://www.ncbi.nlm.nih.gov/pubmed/15855812

Parenteral iron therapy in cancer-associated anemia

Hematology Am Soc Hematol Educ Program 2010; 2010:351-6

Henry DH.

http://asheducationbook.hematologylibrary.org/content/2010/1/351.long

The burden of blood transfusion: a utilization and economic analysis–a pilot study in patients with chemotherapy-induced anemia (CIA)

J Med Econ 2013; 16(5):633-8

Reitan JF

http://www.ncbi.nlm.nih.gov/pubmed/23425291

Venous Thromboembolism and Mortality Associated With Recombinant Erythropoietin and Darbepoetin Administration for the Treatment of Cancer-Associated Anemia

Charles L. Bennett, MD, PhD

JAMA 2008; 299(8):914-924

http://jama.jamanetwork.com/article.aspx?articleid=181533

Clinical Use of Intravenous Iron: Administration, Efficacy, and Safety

Michael Auerbach and Harold Ballard

Hematology Am Soc Hematol Educ Program 2010; 2010:338-47

http://asheducationbook.hematologylibrary.org/content/2010/1/338.full.pdf

 Incidence and risk factors for the development of anemia following gastric bypass surgery

World J Gastroenterol Apr 21, 2010; 16(15): 1867–1870

Dimitrios V Avgerinos

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856827/

Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation

Biomed Res Int. 2013; 2013: 205467

Mingyi Chen, et al

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741944/

Profile of altered brain iron acquisition in restless legs syndrome

Connor JR, Ponnuru P, Wang XS, Patton SM, Allen RP, Earley CJ.

Brain 2011 Apr; 134(Pt 4):959-68

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069701/pdf/awr012.pdf

Prevalence of anaemia in older persons: systematic review

Gaskell H, Derry S, Andrew Moore R, McQuay HJ

BMC Geriatr 2008 Jan 14; 8:1

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248585/pdf/1471-2318-8-1.pdf

Intermittent iron supplementation for improving nutrition and development in children under 12 years of age

Luz Maria De-Regil, et al

Cochrane Database Syst Rev. 2011; (12): CD009085

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547491/

 

http://kidshealth.org/teen/diseases_conditions/blood/anemia.html